Los Angeles Chargers
Buffalo Bills
Kickoff: 1:00 PM
New Highmark Stadium, Orchard Park
Match Facts
- League
- National Football League
- Week
- Week 3
- Date
- 09/27/2026
- Venue
- New Highmark Stadium
The Buffalo Bills host the Los Angeles Chargers at New Highmark Stadium in Orchard Park on Sunday, September 27, a Week 3 date that puts two of the AFC’s deeper rosters under one roof. Buffalo closed the 2025/26 season 12-5 with 481 points scored, while the Chargers went 11-6 as the AFC West’s runner-up with the stingier defense of the pair, allowing 340. Both walked out of January with a playoff loss and into a fresh campaign, which makes this the kind of Sunday worth circling on the calendar.
Buffalo’s ground game ran for 4.9 yards a carry and 32 touchdowns last season, and the Chargers’ defense allowed 4.3 a carry and 340 points, the sharpest contrast on the board when these two line up in Week 3.
Last season’s form
The Bills wrapped the 2025/26 season at 12-5 with a last-five line of L-W-W-L-W, putting up 481 points against 365 allowed. The Chargers went 11-6 in the AFC West and closed L-L-L-W-W, with 368 points scored and 340 conceded on the year. Two double-digit-win campaigns, two fresh starts, and an early-season answer waiting to be written.
Offense vs defense
Buffalo’s offense ran for 4.9 yards a carry with 32 rushing touchdowns and 4,210 passing yards, a balance that keeps opponents honest. Los Angeles, meanwhile, built its season on the other side of the ball: 4.3 yards allowed per carry, 1,653 rushing yards surrendered, 17 passing scores given up, 50 sacks, and 20 interceptions. That front against that ground game is the matchup within the matchup.
The January finish
Neither club stretched its January run very far. The Bills ended with a 30-33 loss to Denver, and the Chargers bowed out 3-16 to New England, so both camps carried the taste of an early exit through the summer. September 27 at New Highmark Stadium is the first chance either side gets to open the next chapter, and there is a seat open for anyone who wants to watch it up close.
When do the Bills host the Chargers in Week 3?
The two meet Sunday, September 27, at 1:00 p.m. ET at New Highmark Stadium in Orchard Park, with Buffalo as the home side.
How did the Bills fare in the 2025/26 season?
Buffalo went 12-5, finished second in the AFC East, scored 481 points, allowed 365, and closed the season with a last-five form line of L-W-W-L-W.
How did the Chargers fare in the 2025/26 season?
Los Angeles went 11-6 as the AFC West runner-up, scored 368 points, allowed 340, and finished with a last-five form line of L-L-L-W-W.
Which defense allowed fewer points last season?
The Chargers surrendered 340 points to Buffalo’s 365, and they allowed 4.3 yards per carry against the Bills’ 5.0.
How did each team end last season?
Both exited in January – the Bills lost 30-33 to Denver, and the Chargers lost 3-16 to New England.
Next Match
Week 3 · New Highmark Stadium · Los Angeles Chargers vs Buffalo Bills
Regular Season NFL match-ups by week 272 games ▾
▼ Week 1 16 games
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Thu, Sep 10 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Sun, Sep 13 |
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Mon, Sep 14 |
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Date TBD |
▼ Week 2 16 games
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Thu, Sep 17 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Sun, Sep 20 |
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Mon, Sep 21 |
▼ Week 3 16 games
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Thu, Sep 24 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Sun, Sep 27 |
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Mon, Sep 28 |
▼ Week 4 16 games
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Thu, Oct 1 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Sun, Oct 4 |
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Mon, Oct 5 |
▼ Week 5 15 games
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Thu, Oct 8 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Sun, Oct 11 |
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Mon, Oct 12 |
▼ Week 6 14 games
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Thu, Oct 15 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Sun, Oct 18 |
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Mon, Oct 19 |
▼ Week 7 14 games
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Thu, Oct 22 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Sun, Oct 25 |
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Mon, Oct 26 |
▼ Week 8 14 games
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Thu, Oct 29 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Sun, Nov 1 |
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Mon, Nov 2 |
▼ Week 9 15 games
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Thu, Nov 5 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Sun, Nov 8 |
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Mon, Nov 9 |
▼ Week 10 14 games
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Thu, Nov 12 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Sun, Nov 15 |
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Mon, Nov 16 |
▼ Week 11 13 games
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Thu, Nov 19 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Sun, Nov 22 |
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Mon, Nov 23 |
▼ Week 12 16 games
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Wed, Nov 25 |
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Thu, Nov 26 |
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Thu, Nov 26 |
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Thu, Nov 26 |
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Fri, Nov 27 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Sun, Nov 29 |
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Mon, Nov 30 |
▼ Week 13 14 games
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Thu, Dec 3 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Sun, Dec 6 |
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Mon, Dec 7 |
▼ Week 14 15 games
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Thu, Dec 10 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Sun, Dec 13 |
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Mon, Dec 14 |
▼ Week 15 16 games
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Thu, Dec 17 |
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Sat, Dec 19 |
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Sat, Dec 19 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Sun, Dec 20 |
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Mon, Dec 21 |
▼ Week 16 16 games
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Thu, Dec 24 |
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Fri, Dec 25 |
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Fri, Dec 25 |
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Fri, Dec 25 |
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Sat, Dec 26 |
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Sun, Dec 27 |
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Sun, Dec 27 |
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Sun, Dec 27 |
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Sun, Dec 27 |
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Sun, Dec 27 |
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Sun, Dec 27 |
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Sun, Dec 27 |
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Mon, Dec 28 |
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Date TBD |
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Date TBD |
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Date TBD |
▼ Week 17 16 games
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Thu, Dec 31 |
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Sat, Jan 2 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Sun, Jan 3 |
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Mon, Jan 4 |
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Date TBD |
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Date TBD |
▼ Week 18 16 games
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Sun, Jan 10 |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |
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Date TBD |